The party discovers they have landed on the shores of Malta (v. 1). They are warmly received and greeted by the indigenous or "native people." Shortly after, Paul is bitten by a snake (v. 3), but he swiftly shakes it off into a fire (v. 5). The locals immediately assume that someone who survives a shipwreck only to be bitten by a snake is not simply having a stroke of bad luck, but is being punished for their crimes (v. 4), as per other legends. Believing Paul to be a criminal, they conclude that he has not escaped "Justice." The locals are understandably shocked when Paul doesn't experience any adverse effects and survives. This is the second instance in Acts where Paul is mistaken for a deity due to a supernatural occurrence.

Despite numerous challenges, such as dangerous days at sea, a shipwreck, and even a snake bite, Paul remains steadfast in his ministry. When presented with an opportunity to assist a severely ill local leader, he seizes it. Paul brings restoration to this individual and opens doors for similar acts of compassion (28:8–9). The locals, in turn, exemplify a hospitable community. They welcome and aid the survivors (v. 2) and reciprocate Paul's kindness with honor and provisions (v. 10). Recognizing their goodwill and openness, Paul views it as an open door for further ministry.

Due to God's faithfulness to his promise that Paul would travel to Rome, the ship's company was protected. The irony of the image of twin gods on the ship bound for Rome is noted. The credit does not belong to fate or the gods, but rather to the Lord who has promised, provided, and protected them throughout the journey to Rome, despite the challenges. The itinerary includes multiple stops, highlighting the ease of their movement (vv. 12-13). Luke acknowledges the presence of believers in Puteoli (v. 14). As they approach Rome (28:15), Christians come out to welcome them. The gospel has already spread across the Mediterranean to Rome, the political, social, and cultural hub of the Western world—in essence, the farthest reaches of the earth.

While in Rome, Paul is confined to his house and under the guard of a single soldier (v. 16). This arrangement allows him to receive visitors and openly share his teachings. Paul concludes his time in Rome with final meetings with Jews. He recounts his experiences in Jerusalem, emphasizing his innocence in wrongdoing against his fellow Jews or Jewish doctrine. He also discloses that the Roman authorities found no grounds for a capital offense against him. He is only in Rome because he appealed to Caesar to avoid the unfounded accusations made by the Jews (Acts 28:17–19).

Paul's objective regarding the Roman Jews is to present his side of the case and share the gospel. His approach in Rome aligns with his previous strategies involving engaging with his fellow Jewish brethren. However, since he cannot attend the synagogue, he brings the synagogue to him. In addition to highlighting that his current situation is due to the hope of Israel, he aims to emphasize Jesus as the fulfillment of all the Scriptures. After years, Paul encounters Jews unaware of his past experiences and teachings. They have only heard about the "sect" condemned elsewhere and are eager to listen to Paul's teachings (Acts 28:22).

In the book of Acts, we discover a final, definitive statement regarding the Jews' rejection and a message of hope for the Gentiles. Salvation will reach the Gentiles, and they will embrace it. The mission to spread the message to the farthest corners of the world will continue. Despite his imprisonment, Paul fearlessly proclaims the kingdom of God and teaches about the Lord Jesus Christ, unhindered and with great boldness (Acts 28:31). Throughout the book of Acts; the kingdom thrives despite persecution, violence, imprisonment, opposition, mobs, hurricanes, and shipwrecks. The growth of the kingdom is not merely in spite of suffering, but it is accomplished and fulfilled through suffering.